What's the difference between Botox, Dysport, and Letybo?

All three are FDA-approved neurotoxins with similar safety and efficacy. Dysport may have slightly faster onset and greater diffusion. Letybo is the newest option with comparable results. Dr. Cappel, MD, will recommend the best option for your needs.

How often do I need treatments?

Most patients return every 3-4 months for maintenance treatments to sustain results.

Can I combine neurotoxins with other treatments?

Yes. Neurotoxins work synergistically with dermal fillers, laser treatments, and medical-grade skincare for comprehensive facial rejuvenation.

Are neurotoxins safe?

Yes. Neurotoxins have been used for decades with an excellent safety profile when administered by qualified practitioners.

Will I look frozen or unnatural?

When performed by an experienced injector like Dr. Cappel, MD, results appear natural and refreshed while maintaining facial expressiveness.

A woman with a smooth, refreshed forehead and expressive eyes, illustrating the natural results of neurotoxin treatments at Dermagnify in Ponte Vedra Beach, Florida

Neurotoxins in Ponte Vedra Beach

Treatment Length:

10-30 minutes

Results Duration:

3-4 months

Downtime:

None

Table of Contents

At Dermagnify in Ponte Vedra Beach, FL, we offer FDA-approved neurotoxin treatments that safely and precisely relax specific facial muscles to reduce the appearance of dynamic wrinkles and refresh your appearance. Also known as neuromodulators or wrinkle relaxers, neurotoxins are among the most trusted and widely used minimally invasive treatments in modern dermatology.

Under the care of Dr. Mark A. Cappel, MD, we offer three of the most advanced neurotoxin options available today: Dysport, Botox, and Letybo. Each is thoughtfully selected based on your goals, anatomy, and treatment history to deliver natural, refreshed results.

We proudly serve patients across Ponte Vedra Beach, Nocatee, Jacksonville, and St. Augustine, FL. Whether this is your first neurotoxin treatment or you are looking for a more customized, medically supervised experience, our team designs plans that reflect your natural features and aesthetic preferences.

At Dermagnify, our approach is results-driven, not units-driven. Rather than pricing treatments by the number of units injected, we structure them around specific treatment areas and the outcomes you want to achieve. This ensures every patient receives the right dose for their anatomy and goals, delivering a natural, refreshed result.

Neurotoxin Treatments at Dermagnify

Neurotoxin treatments are injectable procedures that use purified botulinum toxin type A to temporarily relax specific facial muscles responsible for creating dynamic wrinkles.

When injected in precise, controlled doses, neurotoxins block the release of acetylcholine—a neurotransmitter that signals muscles to contract. By preventing these muscle contractions, neurotoxins allow the overlying skin to smooth out, reducing the appearance of existing wrinkles and preventing new lines from forming.

Neurotoxins address this process by temporarily weakening the muscles that create the expression lines. When injected into specific facial muscles, the neurotoxin blocks nerve signals that cause muscle contraction. The targeted muscles relax, allowing the overlying skin to smooth out. The effect is temporary, lasting approximately 3-4 months, after which muscle activity gradually returns and repeat treatment is needed to maintain results.

Choosing between Dysport and Botox? Our complete comparison covers onset, diffusion, unit conversion, and when Dr. Cappel recommends each.

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Our Neurotoxins

At Dermagnify, we offer three FDA-approved neurotoxins. Each has slightly different characteristics, allowing Dr. Cappel to select the option that best matches your anatomy, treatment history, and desired outcome.

Dysport®

*Recommended – Dr. Cappel's preferred neuromodulator

The Fast-Acting Alternative — AbobotulinumtoxinA

Learn more about Dysport at Dermagnify

FDA-approved since 2009, Dysport offers a fast onset (typically 2–5 days) and spreads more diffusely, which makes it particularly well suited for treating larger areas such as the forehead. Dr. Cappel's preferred neuromodulator for most patients, and a popular option for those who want to see results quickly.

Botox®

The Original — OnabotulinumtoxinA

Learn more about Botox at Dermagnify

The most studied and widely used neurotoxin worldwide. FDA-approved since 2002, Botox provides predictable, precise results for expression lines including forehead lines, frown lines (11s), and crow's feet. Excellent for both first-time patients and long-term treatment plans.

Letybo®

The Newest Generation — LetibotulinumtoxinA

Learn more about Letybo at Dermagnify

The most recent FDA-approved neurotoxin (2024), specifically studied for glabellar lines (11s). Manufactured to a high purity standard, Letybo has quickly gained recognition for consistent results and a favorable safety profile. An excellent option for patients seeking the newest generation of the technology.

Dysport®, Botox® & Letybo®: How They Compare

Each of these neurotoxins is safe, FDA-approved, and clinically effective. The table below highlights their key differences.

During your consultation, Dr. Cappel will recommend the option best suited to your goals and anatomy.

Treatment	Primary Target	Mechanism of Action	Best For
Dysport®	Larger treatment areas, faster onset	AbobotulinumtoxinA (FDA 2009). Broader diffusion, 2-5 day onset	Larger areas like the forehead, when a quicker onset is preferred
Botox®	Dynamic wrinkles, expression lines	OnabotulinumtoxinA (FDA 2002). Precise, targeted diffusion for accurate placement	Precise dosing, established results, off-label uses (masseter, hyperhidrosis, TMJ)
Letybo®	Glabellar lines (11s), newest formulation	LetibotulinumtoxinA (FDA 2024). High-purity manufacturing standard	Patients seeking the newest generation of the technology

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Treatment by Concern

Neurotoxins address a range of expression lines and functional concerns. Below is what to expect for each of the most common treatment areas.

Dr. Cappel personalizes dosing based on your anatomy and goals.

Concern	Muscle Targeted	Typical Units	Best For
Forehead Lines	Frontalis	10–20	Horizontal lines that appear when raising the eyebrows
Frown Lines (11s)	Corrugators + procerus	20–25	Vertical lines between the brows
Crow's Feet	Orbicularis oculi	10–12 per side	Lines fanning from the outer corners of the eyes
Brow Lift	Depressor supercilii	4–6 per side	Non-surgical elevation of the brow area
Neck Bands	Platysma	20–40	Vertical bands visible on the front of the neck

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DETAILED
BREAKDOWN

Below each concern is explained in more detail, including the anatomy involved and the mechanism of treatment.

Forehead Lines

Forehead lines are the horizontal creases that appear when you raise your eyebrows. They form gradually over years of expressive movement of the frontalis muscle, the broad, flat muscle that lifts the brow.

Precise, low-dose neurotoxin injections relax the frontalis just enough to soften the lines without freezing expression. The typical treatment uses a Dysport dose equivalent to 10 to 20 units of Botox, depending on muscle strength and how much movement you want to preserve. Results appear within 3 to 7 days and typically last 3 to 4 months.

Dr. Cappel starts conservatively and refines dosing at follow-up visits, so your look remains natural rather than heavy or immobile. See Pricing for the current cost per area.

Frown Lines (the "11s")

The vertical lines between the eyebrows, often called the "11s," form from repeated frowning, concentrating, or squinting. They involve two muscle groups: the corrugator supercilii (which pulls the brows inward) and the procerus (which pulls the brows down at the bridge of the nose).

Standard treatment involves a Dysport or Letybo dose equivalent to 20 to 25 units of Botox, distributed across five injection points. Letybo, in particular, is FDA-approved specifically for glabellar lines. Results begin within 2 to 7 days and last 3 to 4 months.

Frown line treatment often produces the most dramatic visible improvement of any single neurotoxin area, since these lines tend to make you appear tired, tense, or older than you feel.

Crow's Feet

Crow's feet are the fine lines that fan outward from the outer corners of the eyes when you smile or squint. They involve the orbicularis oculi muscle, a delicate circular muscle that closes the eyelids.

Because of the anatomy in this area, dosing is smaller and placement is precise: typically 10 to 12 units per side (20 to 24 units total), injected superficially in two to three points fanning out from the outer corner of the eye. Results are noticeable within 3 to 5 days and last 3 to 4 months.

Dr. Cappel aims to soften the lines while preserving a natural smile. Overtreatment in this area can flatten the smile, which is why placement matters as much as dose.

Non-Surgical Brow Lift

A non-surgical brow lift uses strategically placed neurotoxin to relax the muscles that pull the brows down (the depressor supercilii and the outer fibers of the orbicularis oculi), allowing the frontalis muscle to gently elevate the brow.

The result is a subtle 1 to 2 mm lift and a more open, rested eye area, achieved with just 4 to 6 units per side. This technique is often combined with frown line and crow's feet treatment for a comprehensive upper-face refresh.

A neurotoxin brow lift is ideal for patients with mild brow descent who want to look more awake without surgery. For more significant brow ptosis, Dr. Cappel may recommend combining neurotoxin with dermal filler or discussing ultrasound tightening with Sofwave.

Neck Bands (Platysmal Bands)

The vertical bands that become visible on the neck with age, weight loss, or muscle tension are formed by the platysma muscle, a thin sheet of muscle that runs from the collarbones to the jaw. As the platysma loses tone, its edges become visible as prominent vertical cords.

Neurotoxin injections placed strategically along the bands (typically 20 to 40 units total) relax the platysma, softening the visible cords and creating a smoother neck contour. Results develop over 1 to 2 weeks and last 3 to 4 months.

For patients whose main concern is skin laxity rather than muscle bands, Dr. Cappel may recommend Sofwave or Exion RF Microneedling as a complementary or alternative approach.

Benefits of Neurotoxin Treatments

Smooths Dynamic Wrinkles

Effectively reduces forehead lines, frown lines, crow's feet, and other expression lines for a smoother, more youthful appearance.

Prevents New Wrinkles from Forming

Regular treatments reduce repetitive muscle contractions, preventing permanent wrinkles from developing.

Natural-Looking Results

When performed by an experienced injector, results appear refreshed and natural, not frozen or overdone.

Versatile Applications

Treats multiple areas of the face and neck, plus medical conditions like hyperhidrosis and migraines.

Enhances Other Treatments

Complements dermal fillers, laser treatments, and skincare for comprehensive facial rejuvenation.

TREATMENT
OVERVIEW

Your Initial Consultation

Dr. Cappel, MD, will evaluate your facial anatomy, discuss your concerns and goals, review your medical history, and recommend a personalized treatment plan. He will explain which areas to treat, expected results, and maintenance schedule.

Pre-Treatment Preparation

Avoid blood-thinning medications and supplements (aspirin, ibuprofen, vitamin E, fish oil) for 1 week before treatment to minimize bruising risk. Arrive with clean skin, free of makeup.

During the Treatment

The treatment area is cleansed. Using a very fine needle, Dr. Cappel, MD, will make precise injections into specific facial muscles. You will feel small pinpricks during injection. No anesthesia is needed, though ice or topical numbing can be used for sensitive patients. Treatment takes 10-20 minutes.

Immediate Aftercare

You may have small bumps or redness at injection sites that resolve within 30-60 minutes. Avoid rubbing or massaging treated areas for 24 hours. Remain upright for 4 hours after treatment. Avoid strenuous exercise, alcohol, and excessive heat for 24 hours.

Results Timeline

Days 3-7: Results begin to appear as muscles gradually relax. Week 2: Full effects are visible. Months 1-3: Results are stable and at their peak. Month 4: Effects gradually diminish as muscle activity returns. Repeat treatment is recommended every 3-4 months for maintenance.

Potential Risks

When performed by an experienced dermatologist, neurotoxin treatments are very safe. Potential risks include temporary bruising (common), mild swelling (common), headache (possible), temporary eyelid or eyebrow drooping (rare, resolves in 2-4 weeks), asymmetry (correctable with additional injections), and allergic reaction (very rare). Dr. Cappel, MD, minimizes risks through precise injection technique and thorough patient evaluation.

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Neurotoxin treatments are suitable for most adults seeking to reduce dynamic wrinkles and maintain a youthful appearance. You may be an ideal candidate if you:

Have moderate to severe forehead lines, frown lines, or crow's feet.
Want to prevent the formation of permanent wrinkles (preventative treatment).
Prefer a non-surgical, minimally invasive approach.
Want natural-looking results that maintain facial expressiveness.
Have realistic expectations about temporary results requiring maintenance.
Are in good overall health with no contraindications.
Want to enhance results from other aesthetic treatments.
Prefer treatments with no downtime.
Are committed to regular maintenance treatments every 3-4 months.
Want to address medical conditions like hyperhidrosis or migraines.

Contraindications:

Neurotoxin treatments may not be suitable for individuals with neuromuscular disorders (myasthenia gravis, ALS), allergies to botulinum toxin or albumin, active skin infections at injection sites, or those who are pregnant or breastfeeding. Certain medications (aminoglycosides, anticoagulants) may increase risks. Dr. Cappel, MD, will review your medical history to ensure neurotoxin treatment is safe and appropriate for you.

Pricing

At Dermagnify, our approach to neuromodulator pricing is Results Driven, not Units Driven. Rather than charging per unit of toxin injected, we structure treatments around specific areas and the outcomes you want to achieve. This ensures every patient receives the right dose for their anatomy and goals — you pay for the result, not for a unit count.

Upper Face Refresh Packages

Our signature Upper Face Refresh packages address the three primary upper-face concern areas (forehead lines, frown lines, and crow's feet). Choose a targeted single-area treatment, a two-area combination, or the full Upper Face Refresh across all three areas

Package	Regular Price	VIP Member Price
Targeted Treatment (one area)	$350	$300
Two Treatment Areas	$600	$500
Upper Face Refresh (all three areas)	$750	$600
Bring a Friend! Refresh Together (per person)	$600 ea	$500 ea

What's Included in Every Treatment

Every neuromodulator package at Dermagnify includes:

Personalized facial assessment
Customized treatment plan
Follow-up evaluation in 1 to 2 weeks
Enhancement or touch-up if needed

Additional Premium Treatment Areas

Beyond the upper face, we offer neuromodulator treatments for a range of additional areas. Each is priced individually based on the anatomy involved.

Treatment Area	Starting Price
Neck Bands (platysma)	$450
Masseters (jaw slimming)	$600
Lip Flip	$150
Bunny Lines	$150
DAO (corners of mouth)	$150
Mentalis (chin dimpling)	$150

VIP Member pricing is available for premium treatment areas — ask our team for details.

VIP Member prices shown above are unlocked through DermagnifyVIP, our $20/month membership powered by RepeatMD. Learn more about DermagnifyVIP and join.

Why Choose Dermagnify for Neurotoxins in Ponte Vedra Beach

Advanced dermatology, delivered with precision, personalization, and purpose.

At Dermagnify, your skin is never treated with a one-size-fits-all approach. Under the leadership of double board-certified dermatologist and dermatopathologist Dr. Mark A. Cappel, MD our practice combines deep medical expertise with advanced imaging technology to deliver truly customized care.

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Double Board-Certified Expertise

Comprehensive Skin Analysis

Evidence-Based Care

Customized Treatment Plans

Medical & Aesthetic Dermatology

Patient-Focused Approach

Related Treatments

For optimal, comprehensive results, this treatment can be safely combined with other advanced aesthetic and wellness services offered at Dermagnify as part of a personalized plan.

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Sofwave (Ultrasound Tightening)

Non-surgical ultrasound treatment for skin laxity that pairs beautifully with neurotoxins. While neurotoxins relax expression muscles, Sofwave lifts and tightens the underlying skin.

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Medical-Grade Skincare

Essential for maintaining skin health and maximizing results from neurotoxin treatments.

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Aerolase Laser Treatments

The Aerolase platform (Neo, Era, and Reverse) addresses skin quality, texture, tone, and pigmentation. Combining Aerolase with neurotoxins creates comprehensive rejuvenation.

What are neurotoxins and how do they work?

Neurotoxins (also called neuromodulators or wrinkle relaxers) are purified proteins that temporarily block nerve signals to targeted facial muscles. When injected in small, precise amounts, they relax the muscles that create expression wrinkles, allowing the overlying skin to smooth out. The three FDA-approved neurotoxins offered at Dermagnify are Dysport, Botox, and Letybo.

What is the difference between Dysport, Botox, and Letybo?

All three are FDA-approved neurotoxins with the same fundamental mechanism, but they differ in formulation, onset speed, and diffusion pattern. Dysport (FDA-approved 2009) has a fast onset and diffuses more broadly, making it well suited for larger areas like the forehead, and is Dr. Cappel's preferred option for most patients. Botox (2002) is the most established and provides precise, targeted results. Letybo (2024) is the newest generation, specifically studied for glabellar lines (11s). Dr. Cappel selects the option best matched to your anatomy and goals.

Why does Dermagnify price by area rather than by unit?

Our approach is results-driven, not units-driven. We structure treatments around specific areas and the outcomes you want to achieve, rather than counting units of toxin injected. This aligns pricing with results and ensures every patient receives the right dose for their anatomy and goals.

How long before I see results?

Initial results begin appearing within 2 to 7 days depending on the product used. Dysport and Letybo typically show earlier onset (2 to 5 days), while Botox may take slightly longer (3 to 7 days). The full effect is visible in 10 to 14 days.

How long do results last?

Neurotoxin results typically last 3 to 4 months for all three products. Duration varies based on individual metabolism, muscle strength, dosing, and area treated. Regular maintenance treatments every 3 to 4 months help sustain results and may allow for lower doses over time.

Does it hurt?

Most patients describe neurotoxin injections as a brief pinch or slight sting. Ultra-fine needles are used, and topical numbing cream is available upon request. The treatment is typically completed in 10 to 20 minutes with minimal discomfort.

Are there side effects?

Neurotoxins are considered very safe when administered by a board-certified dermatologist. Common, temporary side effects include mild redness or small bumps at injection sites that resolve within an hour. Less common effects include mild bruising or headache. Rare effects (such as temporary eyelid or brow droop) can occur but resolve as the product wears off. There is no downtime, and most patients return to normal activities immediately.

Am I too young for neurotoxins?

Preventative neurotoxin use has become increasingly common in patients in their 20s and early 30s. When used early and conservatively, it may help delay the formation of deeper static wrinkles by relaxing the muscles that create them. Dr. Cappel evaluates each patient individually to determine whether preventative treatment is appropriate.

Can I have neurotoxins if I am pregnant or breastfeeding?

Neurotoxin treatments are not recommended during pregnancy or breastfeeding. Postpone treatment until after breastfeeding is complete, then schedule a consultation to resume.

Why choose a dermatologist over a med spa?

A board-certified dermatologist offers deep anatomical knowledge, familiarity with the full range of skin conditions, and the ability to manage any complications directly. At Dermagnify, Dr. Cappel personally administers all neurotoxin treatments, ensuring consistent, expert care under medical oversight.

Can neurotoxins be combined with fillers or lasers?

Yes, and combining treatments is common. Neurotoxins are frequently paired with dermal fillers (which restore volume) or with laser treatments such as Aerolase (which improve skin quality) for comprehensive rejuvenation. Dr. Cappel sequences treatments for optimal, safe results.

Do you offer a Membership program?

Yes. Our DermagnifyVIP program is a monthly membership powered by RepeatMD. For $20 per month, members unlock preferred pricing on all neurotoxin packages, plus additional benefits across the practice.

Can neurotoxins be used for things other than wrinkles?

Yes. Common off-label and additional FDA-approved uses include treatment of excessive underarm sweating (hyperhidrosis), jaw slimming and TMJ relief (masseter), lip flip, and platysmal neck bands. Dr. Cappel offers all of these applications at Dermagnify.

Are you ready to refresh your look with a personalized neurotoxin treatment?

Contact Dermagnify, Medical, Surgical and Cosmetic Dermatology in Ponte Vedra Beach, FL today to schedule your consultation with Dr. Mark A. Cappel, MD. Every plan begins with a comprehensive Alma IQ® skin analysis and personalized recommendations for Dysport, Botox, or Letybo.

Location: 100 Executive Way, Suite 114, Ponte Vedra Beach, FL 32082

Email: info@dermagnify.com

Phone: (904) 686-7771